Replacing the in-line filter cartridge on the primary check valve

Replacing the in-line filter cartridge on the primary check valve
Topic LCI-USG-0161, Last Updated 11/08/2024

Users or Waters field service personnel can replace the in-line filter cartridge on the pump primary check valve.

Warning: Observe Good Laboratory Practice (GLP) at all times, particularly when working with hazardous materials. Consult the Safety Data Sheets regarding the solvents you use. Additionally, consult the safety representative for your organization regarding its protocols for handling such materials.
Note: To avoid contaminating system components, wear clean, chemical-resistant, powder-free gloves when performing this procedure.

Required tools and materials

  • Chemical-resistant, powder-free gloves
  • Replacement in-line filter cartridge

To replace the in-line filter cartridge on the primary check valve:

  1. Flush the pump with nonhazardous solvent.
  2. Power-off the system.
  3. Open the pump compartment door.
  4. Hold the ferrule holder fitting while unscrewing and remove the cap nut from the fitting.
    Figure 1: Unscrewing the cap nut and ferrule holder
    Ferrule holder fitting
    Cap nut
    Figure 2: Removing the cap nut from the ferrule holder
    Ferrule holder fitting
    Cap nut
  5. Slide the cap nut down the tube and disengage the filter from the ferrule holder fitting.
    Figure 3: Pulling the cap nut from the tube
    In-line filter cartridge
    Cap nut
    Tube
    Figure 4: In-line filter cartridge, locking ring, and cap nut
    In-line filter cartridge
    Metal locking ring
    Cap nut
    Tube
  6. Slide the metal locking ring downward off the in-line filter cartridge and slide the cartridge off the tube.
  7. Inspect the filter cartridge to determine whether it is constructed of stainless steel or titanium (Ti), and ensure that you have the correct replacement cartridge. No marking indicates a filter cartridge constructed of stainless steel, and "Ti" indicates a filter cartridge constructed of titanium.
  8. Slide the cap nut over the end of the tube.
    Figure 5: Sliding cap nut on tube
    Cap nut
    Tube
  9. Slide the metal locking ring onto the tube, ensuring that the thicker end of the metal locking ring faces toward the cap nut.
    Figure 6: Sliding metal locking ring on tube
    Metal locking ring
    Thicker end of metal locking ring facing toward cap nut
    Tube
    Cap nut
  10. Unpack the new in-line filter cartridge.
  11. Place the new in-line filter cartridge onto the end of the tube.
    Figure 7: Placing in-line filter cartridge onto end of tube
    In-line filter cartridge
    Tube
    Cap nut
  12. Verify that the cartridge is bottomed out in the tube, and then slide the metal locking ring onto the boss on the bottom of the in-line filter cartridge while making sure the tube stays bottomed out.
  13. Insert the in-line filter cartridge with tubing into the ferrule holder fitting, finger-tighten the cap nut until it bottoms out, and then tighten it 1/4-turn.
    Figure 8: Installing the cap nut on the ferrule holder fitting
    Ferrule holder fitting
    Cap nut
  14. Close the pump compartment door.
  15. Power-on the system.
  16. Prime the pump.

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To avoid risk of personal injury and to prevent damage to laboratory equipment, always operate your Waters products in accordance with the applicable operational and safety information, your organization’s standard operating procedures, and local regulations.

Refer to the English version of this page for the latest information.

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